Andrés Klein

Prof. Andrés Klein’s research interests include uncovering the genetic and cellular basis of phenotypic variability as a way for identifying novel therapeutic targets for diseases with lysosomal dysfunction including Parkinson’s disease. To this end he uses population based approached in yeast, flies, mice and humans. His work has led to the discovery of potential treatments for two genetic diseases (Niemann-Pick C and neuropathic Gaucher disease), using FDA-approved drugs.

Andrés Klein received his B.Sc in Biochemistry and his PhD in Cellular and Molecular Biology at the Pontificia Universidad Católica de Chile. Dr. Klein did a postdoc at Stanford University (2009-2011) and a second postdoc (2011-2015) at the Weizmann Institute of Science in Israel. Currently he is the Director (Head) of the Center for Genetics and Genomics at the Universidad del Desarrollo (UDD) in Chile, where he is applying system biology approaches for the identification of modifier genes of disease progression and biomarkers (precision medicine).