Bruce Given

Dr. Given is CEO of Leonardo Biosystems, serves as a Healthcare Products Consultant as the Principal of Bruce Given Consulting and is Chairman of the Board for ICON, plc. (Nasdaq: ICLR). Until June of 2007, Dr. Given served as President and Chief Executive Officer and as a member of the Board of Directors of Encysive Pharmaceuticals, which he joined in 2002. Prior to joining Encysive Pharmaceuticals, he was with Johnson & Johnson for 9 years, serving in several capacities including as President, International, Ortho-Clinical Diagnostics and as Group Vice President, Head of U.S. Marketing & Sales, Research & Development for Janssen Pharmaceutica.