Dr. Boyle’s research uses advanced techniques in quantitative pharmacology and clinical trial design to improve the use of narrow therapeutic drugs in pediatric patients requiring chemotherapy and immunosuppression for the treatment of cancer, hematopoietic cell transplantation, and gene therapy. Dr. Boyle aims to optimize complex drug therapy in children undergoing treatment for a life-threatening diseases, in part by reducing the technical barriers of implementing and adopting population pharmacokinetic models into routine clinical practice.