James Digregori

Member of the SAB. Dr. DeGregori currently is a Professor in the Department of Biochemistry and Molecular Genetics and the Associate Director for Basic Research at the University of Colorado Cancer Center. His lab is working to understand the evolution of cancers and to identify cancer cell vulnerabilities that could be exploited therapeutically, with a focus on leukemia. He has been a member of the CMI-B and TWD-A NIH study sections, has served on numerous grant panels (NIH/NCI, HHMI and private foundations), and is an associate editor for Molecular Cancer Research. Dr. DeGregori has more than 100 publications in high quality journals (Nature, Cancer Cell, PLoS Biology, PNAS, Cancer Research, JCI, etc.), and a continuous record of peer-reviewed extramural research funding. His lab is currently supported by 2 R01s, 1 R21, and a Lung SPORE project (all from the NCI). The expertise of the DeGregori lab is broad, ranging from the basic biochemistry, to molecular genetics/genomics, to evolutionary biology, to computational biology, to pre-clinical mouse models for the development of cancer therapeutics. He received his B.A. in Microbiology from the University of Texas Austin in 1987 and his Ph.D. in Biology from MIT in 1993. Dr. DeGregori did his postdoctoral fellowship in genetics at Duke University Medical Center.