NBE-Therapeutics is developing best-in-class cancer therapies to increase survival and improve quality of life for cancer patients worldwide. The company’s next-generation immune-stimulatory therapies are based on a proprietary, highly differentiated Antibody-Drug Conjugate (ADC) platform. This best-in-class ADC platform creates highly potent and safe immune-stimulatory ADCs ("iADCs™") with an anthracycline payload, not only directly targeting tumor cells, but also inducing a long-lasting immunological anti-tumor effect. The company’s lead asset, NBE-002, an anti-ROR1 ADC, is due to start first-in-human clinical trials in three US centers by the end of 2020, focusing on triple negative breast cancer, but also other solid cancer indications which express ROR1.

NBE-Therapeutics is a privately owned biotech company based in Basel, financed by Germany’s Boehringer Ingelheim Venture Fund, the Czech Republic’s PPF Group and Denmark’s Novo Holdings as international institutional investors, and by Swiss, German, and Dutch private investors. The company has raised over USD 65m, including a USD 22m Series C (2020), two USD 20m Series B rounds (2016 & 2018), a USD 3m Series A (2015), and over USD 4m from several non-dilutive grants from organizations including the Swiss Commission for Technology & Innovation, the European Commission, and Systems-X.

Biotechnology

NBE Therapeutics

Jean Engela

Florian Durante

Ulrike Fiedler

Mariarosa Spina Horn

Marco Meier

Ina Hellmann

Giuliano Bellapadrona

Cornelia Baumgartner- Diolaiuti

Carl Deutsch, PhD, MBA

Hüseyin Birogul

Flavio Solca

Gerd Munzert

The Research and Development Team at NBE Therapeutics is dedicated to advancing the company's innovative ADC platform and developing cutting-edge cancer therapies. This team conducts rigorous preclinical research, formulates and tests novel iADCs™, and collaborates closely with clinical teams to ensure a smooth transition to human trials. Their work is vital in identifying new therapeutic targets and optimizing existing assets to enhance the efficacy and safety of cancer treatments, ultimately aiming to improve outcomes for patients with difficult-to-treat tumors.

Research and Development Team

Leadership Team

Clinical Operations Team

Research and Development Team

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Leadership Team

Clinical Operations Team