David G. Denardo

Dr. DeNardo is Professor of Medicine, Pathology & Immunology at Washington University School of Medicine, St. Louis. His research is focused on understanding how immune responses shape and are shaped by malignancies. This includes investigating efforts to enhance response to conventional, targeted or immunotherapy treatment approaches. Dr. DeNardo’s research aims to understand the impact of fibrosis on responses to immunotherapy and understanding the effects of macrophage origin on tumor fibrosis, immunity, and regulation of tumor progression. In addition, his work seeks to understand defects in dendritic cell development and trafficking in cancer patients as well as targeting macrophages to unlock responsiveness to immunotherapy.