Robert Knowlton

Dr. Knowlton’s research focuses on discovering advances in clinical neurophysiology and brain imaging that can affect decision-making in treatment of seizure disorders and brain tumors. The main focus of his work is to determine which advanced imaging discoveries should be moved to clinical application. He has worked specifically to improve and validate the clinical utilization of multiple modalities of brain imaging, including high-resolution magnetic resonance imaging (MRI), MR spectroscopy/spectroscopic imaging (MRS/MRSI), positron emission tomography (PET), magnetic and electrical source imaging (MSI/ESI), and ictal single photon emission computed tomography (SPECT). From the very beginning of his career, Dr. Knowlton has taken advantage of combining multiple imaging modalities to allow comparison of the relative merits for each test to determine if novel information can be discerned and measure whether purported advances improve patient care.