Aldo Ciau-Uitz has a rich and diverse work experience. In 1994, they worked as an Assistant Professor in Plant Biology and Biotechnology at the Centro de Investigación Científica de Yucatán, where they focused on investigating the effects of plant growth factors on the production of plant secondary metabolites with anticancer properties. Aldo utilized Catharanthus roseus hairy roots as a model in their research.
From 2000 to 2004, Aldo worked as a Research Fellow at the University of Nottingham, where they investigated the origins of blood stem cells in Xenopus embryos. Specifically, they examined whether yolk sac and dorsal aorta blood cells shared a common origin.
Starting in 2004, Aldo began their tenure at the University of Oxford, initially as an MRC Investigator Scientist in Professor Roger Patient's group. Here, they delved into the ontogeny and development of hematopoietic stem cells in Xenopus embryos, describing the existence of two populations of haemangioblasts and their roles in generating various blood cells.
Subsequently, at the University of Oxford, Aldo took on the role of Investigator Scientist, collaborating with Professor Roger Patient, Professor Tariq Enver, and Professor Catherine Porcher. Aldo aimed to establish the gene regulatory network controlling definitive haemangioblasts identity and differentiation, identifying essential transcription factors and signaling pathways. Aldo utilized various techniques, including genetic manipulations and gain-of-function experiments, to elucidate the molecular mechanisms involved.
In 2019, Aldo became a Senior Scientist at biomodal (formerly known as Cambridge Epigenetix). Aldo joined the Discovery Team, focusing on developing new technologies for simultaneously reading genetic and epigenetic information in DNA. The aim is to integrate their DUET technology with multi-omic technologies to enhance understanding of normal biological processes and disease.
Aldo Ciau-Uitz obtained their Bachelor of Biology degree from the Universidad Autonoma de Yucatan in 1992. Aldo then pursued their Masters in Biotechnology at the Instituto Tecnológico de Mérida from 1991 to 1994, focusing on Plant Biochemistry, Molecular Biology, and Biotechnology. Following this, Aldo completed their Doctor of Philosophy (PhD) in Molecular Biology (Developmental Biology) at King's College London from 1997 to 2001.
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