Mark Ledeboer

Senior Vice President, Drug Discovery at Expansion Therapeutics

Mark Ledeboer is an accomplished drug discovery expert currently serving as Senior Vice President of Drug Discovery at Expansion Therapeutics since June 2021, where the focus is on small molecule medicines for RNA-mediated diseases. Prior experience includes roles at Goldfinch Bio as Vice President of Drug Discovery and Chemistry, and at Vertex Pharmaceuticals as a Research Fellow and Senior Staff Investigator, engaging in various small molecule therapeutic programs and kinase target discovery. Ledeboer began their academic career as a Graduate Research Assistant at Brown University, earning both a PhD in Synthetic Organic Synthesis and a Master's in Organic Chemistry, following an undergraduate degree in Chemistry from Lafayette College. Early research includes significant contributions as an NIH Postdoctoral Fellow at The Scripps Research Institute under Dale L. Boger, concentrating on the synthesis of potent natural products.

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